Cullen corylifolium phenol is an important monoterpene compound extracted from Cullen corylifolium, which has a wide range of pharmacological activities. Many studies have shown that Cullen corylifolium is a potential skin care active ingredient. In particular, Cullen corylifolium phenol has good stability, small side effects, and low skin irritation, so it can be used as a substitute for Retinol.
We know that among common skin care ingredients, Nicotinamide mainly controls oil, salicylic acid mainly exfoliates, and BPO mainly sterilizes.
Cullen corylifolium can be said to have the above effects.
Oil control -- Cullen corylifolium phenol has estrogen like effect, which can inhibit 5- α- The production of reductase inhibits sebum secretion and has an oil control effect.
Antioxidant - Squalene in sebum is oxidized under ultraviolet radiation. The formation of peroxysqualene can stimulate the fragile epidermal layer at the funnel-shaped part of the hair follicle, leading to excessive keratinization. Subsequently, the detached keratinocytes mix with sebum to block the pores, forming angle plugs and acne.
As a fat soluble antioxidant stronger than vitamin E, Cullen corylifolium can effectively protect sebum from peroxidation, thus preventing excessive keratinization of hair follicles.
Antibacterial -- Cullen corylifolium phenol has a good inhibitory effect on Cutibacterium acnes, Staphylococcus aureus, Staphylococcus epidermidis, Candida albicans and other bacteria/fungi on the skin surface.
And it has a synergistic effect when combined with salicylic acid.
In addition, Cullen corylifolium can inhibit the expression of MMP and reduce the damage of MMP to the collagen in the dermis.
From the perspective of mechanism, Cullen corylifolium's cellular signal regulation pathway is very similar to that of retinol, including the regulation of retinoic acid receptor gene, collagen and extracellular matrix synthase.
At the same time, it effectively avoids the drawbacks of retinol:
Cullen corylifolium phenol has good stability and is not afraid of light - so it can also be used in the daytime; At the same time, Cullen corylifolium phenol has less side effects than retinol, and is less irritating to the skin.